Gender, Obstructive sleep apnea, Rapid eye movement
Citation Information :
Haridas N, Sudhakar N, Ashok A, Kunoor A, Bhaskaran R. Prevalence and Clinical Features of Rapid Eye Movement-related Obstructive Sleep Apnea: A Cross-sectional Analysis of Clinical Population from South India. Indian Sleep Med 2023; 18 (1):11-14.
Introduction: Rapid eye movement (REM)-related obstructive sleep apnea (OSA) is a condition where apneas and hypopneas occur predominately during REM sleep. There is limited data on the prevalence of REM-related breathing disorders in the Indian population.
Aim of the study: To estimate the prevalence of REM-related OSA in a clinic-based population in South India.
Methodology: This cross-sectional observational study was done in a tertiary care center in South India from January 2017 to December 2019. Consecutive adult patients who underwent level-I polysomnography were enrolled. Apnea–Hypopnea Index (AHI) was computed as the total number of apneas and hypopneas per hour of total sleep time. Sleep-state-dependent indices were also determined by dividing the number of events in nonrapid eye movement (NREM) and REM sleep by the amount of NREM and REM time, respectively. Patients with an AHI greater than five were diagnosed with OSA and included in this study.
Rapid eye movement-related obstructive sleep apnea was defined as overall AHI ≥5 and AHI REM/AHI NREM ≥2.
Nonrapid eye movement-related OSA was defined as overall AHI ≥5 and AHI REM/AHI NREM ≥2.
Statistical analysis was performed using IBM SPSS version 21.0.
Results: One hundred ninety-nine patients diagnosed with OSA were included in the study. Rapid eye movement OSA has a prevalence of 24.12% in this population. Age >50 years and female sex were the factors associated with REM-predominant OSA, while T88% >20% was associated with NREM OSA.
Conclusion: Rapid eye movement-related OSA is prevalent in South Indian patients referred for evaluation of sleepiness.
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