Indian Journal of Sleep Medicine

Register      Login

VOLUME 14 , ISSUE 1 ( January-March, 2019 ) > List of Articles


Therapeutic Cure of Obesity Hypoventilation Syndrome Resulting in Cure of Obstructive Sleep Apnea and Metabolic Syndrome

Anshul Mittal, Vidushi Rathi

Keywords : Cure, Obesity hypoventilation syndrome, Obstructive sleep apnea

Citation Information : Mittal A, Rathi V. Therapeutic Cure of Obesity Hypoventilation Syndrome Resulting in Cure of Obstructive Sleep Apnea and Metabolic Syndrome. Indian Sleep Med 2019; 14 (1):18-21.

DOI: 10.5005/jp-journals-10069-0034

License: CC BY-NC 4.0

Published Online: 01-03-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Obesity hypoventilation syndrome (OHS) is a highly underdiagnosed and undertreated condition, especially in developing countries like India. We present a case of a young 26-year-old male with Metabolic syndrome along with severe OSA with OHS, who after weight reduction of 50 kgs over 2 years was practically cured of the same; with no requirement of PAP, insulin and oral medications in follow-up. This case highlights the importance of evaluating obstructive sleep apnea by a phenotypic approach so that appropriate treatment is given.

PDF Share
  1. Al Dabal L, BaHammam AS. Obesity hypoventilation syndrome. Ann Thorac Med 2009;4:41-49.
  2. Kessler R, Chaouat A, Schinkewitch P, Faller M, Casel S, Krieger J, et al. The obesity-hypoventilation syndrome revisited: a prospective study of 34 consecutive cases. Chest. 2001 Aug 1;120(2):369-376.
  3. Laaban J-P, Chailleux E. Observatory Group of ANTADIR. Daytime hypercapnia in adult patients with obstructive sleep apnea syndrome in France, before initiating nocturnal nasal continuous positive airway pressure therapy. Chest 2005;127:710-715.
  4. Mokhlesi B, Tulaimat A, Faibussowitsch I, Wang Y, Evans A. Obesity hypoventilation syndrome: prevalence and predictors in patients with obstructive sleep apnea. Sleep Breath 2007;11:117-124.
  5. Kaw R, Hernandez AV, Walker E, Aboussouan L, Mokhlesi B. Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and metaanalysis of cohort studies. Chest 2009;136:787-796.
  6. Mokhlesi B, Saager L, Kaw RQ. Should we routinely screen for hypercapnia in sleep apnea patients before elective non cardiac surgery? Cleve Clin J Med 2010;77:60-61.
  7. Nowbar S, Burkart KM, Gonzales R, Fedorowicz A, Gozansky WS, Gaudio JC, et al. Obesity associated hypoventilation in hospitalised patients: prevalence, impact and outcome. Am J Med 2004;116:1-7.
  8. Subramani Y, Singh M, Wong J, Kushida CA, Malhotra A, Chung F. Understanding Phenotypes of Obstructive Sleep Apnea: Applications in Anesthesia, Surgery, and Perioperative Medicine. Anesth Analg. 2017;124(1):179-191.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.