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VOLUME 5 , ISSUE 4 ( October-December, 2010 ) > List of Articles


Revisiting Kleine-Levin Syndrome – a case report and review

Jyoti Krishna, Ai-Ping Chua, Prakash Kotagal, Chua Ai Ping

Keywords : Hypersomnia, Episodic, Recurrent, Multiple sleep latency test, Polysomnogram, Carbamazepine, Hyperphagia, Kleine-Levin Syndrome.

Citation Information : Krishna J, Chua A, Kotagal P, Ping CA. Revisiting Kleine-Levin Syndrome – a case report and review. Indian Sleep Med 2010; 5 (4):111-115.

DOI: 10.5005/ijsm-5-4-111

License: NA

Published Online: 01-07-2018

Copyright Statement:  NA


A 15 year-old girl who was previously well presented with severe recurrent episodic hypersomnia associated with abnormal behavior and hyperphagia after recovery from a mild upper respiratory tract infection (URTI). Physical examination was unremarkable with normal blood tests, brain imaging and electroencephalogram (EEG). A multiple sleep latency test (MSLT) during a typical episode showed moderate hypersomnolence in contrast to a normal MSLT performed an the interval between episodes. Clinical features were consistent with Kleine-Levin syndrome (KLS). She was started on carbamazepine treatment after failing a trial of methylphenidate and is currently being followed up for her symptoms.

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