Indian Journal of Sleep Medicine

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VOLUME 5 , ISSUE 1 ( January-March, 2010 ) > List of Articles


Prevalence of Obstructive Sleep Apnea in Type 2 Diabetes Mellitus

Charanjit Singh, M K Sen, J. C. Suri, Robert Ekka, Anant Gupta

Citation Information : Singh C, Sen MK, Suri JC, Ekka R, Gupta A. Prevalence of Obstructive Sleep Apnea in Type 2 Diabetes Mellitus. Indian Sleep Med 2010; 5 (1):21-28.

DOI: 10.5005/ijsm-5-1-21

License: CC BY-SA 4.0

Published Online: 01-07-2018

Copyright Statement:  Copyright © 2010; The Author(s).


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  1. Young T, Palta M, Dempsey J etal. The occurrence of sleep disordered breathing among middle-aged adults. N Engl J Med 1993; 328(17):1230-1235.
  2. Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37:1595-1607.
  3. Powers AL. Diabetes Mellitus In: Harrison's Principles of Internal medicine. Fanci AS, Branwald E, Kasper DL (eds). 17th edition. New York, McGraw Hill Medical 2008; 2275- 2304.
  4. Resnick HE, Redline S, Shahar E, Gilpin A, Newman A, Walter R, Ewy GA, Howard BV, Punjabi NM. Diabetes and sleep disturbances; findings from the Sleep Heart Health Study. Diabetes Care 2003; 26:702-709.
  5. Foster GD, Sanders MH, Millman R, Zammit G, etal. Obstructive sleep apnea among obese patients with type 2 diabetes. Diabetes Care 2009; 32:1017-1019.
  6. Einhorn D, Stewart DA, Erman MK, Gordon N et al. Prevalence of sleep apnea in a population of adults with type 2 diabetes mellitus. Endocr Pract 2007; 13:355-362.
  7. Somer S VK, White DP, Amin R et al. Sleep apnea and Cardiovascular disease: an American Heart Association/ American College of Cardiology Foundation Scientific Statement from American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council of Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol 2008; 52:686-717.
  8. Yaggi HK, Concato J, Kernan Wai et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med 2005; 353:2034-2041.
  9. Young T, Finn L, Pepparel PE et al. Sleep disordered breathing and mortality: eighteen-year follow up of the Wisconsin Sleep Cohort. Sleep 2008; 31:14071-1078.
  10. Bradley TD, Floras JS. Obstructive sleep and its cardiovascular consequences. Lancet 2009; 373:82-93.
  11. Flegal KM, Caroll MD, Ogden CL and Johnson CL. Prevalence and trends in obesity among US adults. JAMA.1999;288:1723-1727.
  12. Aronsohn RS, Whitmore H, Van Cauter E, Tasali E. Impact of untreated obstructive sleep apnea on glucose control in Type 2 Diabetes. Am J Respir Crit Care Med 2010; 181:507-513.
  13. Mahmood K, Akhter N, Eldeirawi K et al. Prevalence of type 2 diabetes in patients with obstructive sleep apnea in a multi-ethnic sample. J Clin Sleep Med 2009; 5(3):215- 221.
  14. Marshall NS, Wong KKH, Phillips CL et al. Is sleep apnea an independent risk factor for prevalent and incident diabetes I the Busselton Health Study? J Clin Sleep Med 2009; 5(1):15-20.
  15. Otake K, Sasanabe R, Hasegawa R et al. Glucose intolerance in Japanese patients with obstructive sleep apnea. Inte Med 2009; 48:1863-1868.
  16. Tiengo A, Fadini GP, Avogiro A. The metabolic syndrome, diabetes and lung dysfunction. Diabetes and Metabolism 2008; 34:447-454.
  17. Wilcox I, McNamara SG, Collins FL et al. “Syndrome Z” the interaction of sleep apnea, Vascular risk factors and heart disease. Thorax 1998; 53(Suppl 3):S25-S28.7.
  18. Kostoglou-Athanassiou I, Athanassiou P. Metabolic syndrome and sleep apnea. Hippokratia 2008; 12(2):81- 86.
  19. West SD, Nicoll DJ, Stradling JR. Prevalence of obstructive sleep apnea in men with type 2 diabetes mellitus. Thorax 2006; 61:945 -950.
  20. Polotsky VY, Li J, Punjabi NM, Rubin AE et al. Intermittent hypoxia increases insulin resistance in generically obese mice. J Physiol 2003; 552:253-264.
  21. Tasali E, Leproult R, Ehrmann DA, etal. Slow wave sleep and the risk of type 2 diabetes in humans. Proc Natl Acad Sci USA 2008;105:1044-1049.
  22. Spiegel K, Knutson K, Leproult R et al. Sleep loss: a novel risk factors for insulin resistance and type 2 diabetes. J Appl Physiol 2005; 99:2008-2019.
  23. Bottini P, Redolfi S, Dottorini ML et al. Autonomic neuropathy increases the risk of obstructive sleep apnea in obese diabetes. Respiration 2008; 75:265-271.
  24. Bottini P, Dottorini ML, Cristina Cardons M, Casucci G et al. Sleep-disordered breathing in non obese diabetes subjects with autonomic neuropathy. Eur Respir J 2003; 22:654-660.
  25. Zizi F, Jean-Louis G, Brown CD, Ogedegbe G, Boutin-Foster C, McFarlance SI. Sleep duration and the risk of diabetes mellitus: epidemiologic evidence and pathophysiologic insights. Curr Diab Rep 2010; 10(1):43-47.
  26. Muraki I, Tanigawa T, Yamagishi K, Sakurai S, Ohira T et al. Nocturnal intermittent hypoxia and the development of type 2 diabetes: the Circulatory Risk in communities study (CIRCS). Diabetologica 2010; 53(3):481-488.
  27. Koopman RJ, Swafford SJ, Beard MN, Meadows SE. Obesity and metabolic disease. Prim Care Clin office Pract 2009; 36:257-270.
  28. Babu AR, Herdegen J, Fogelfeld L, Shott S, Mazzone T. Type 2 diabetes, glycemic control and continuous positive airway pressure in obstructive sleep apnea. Arch Intern Med 2005; 165:447-452.
  29. Coughlin SR, Manidsley L, Murgaza JA et al. Obstructive sleep apnea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 2004; 25:735-741.
  30. Peted N, Kassirer M, Shitrit D et al. The association of OSA with insulin resistance, inflammation and metabolic syndrome. Respiratory Med 2007; 101:1696-1701.
  31. Punjabi NM, Brown WD, Erman M, Slade G, Neubauer D, Ferri R, Hong SC, Partinen M, Hines M, Weitz M. Do sleep disorders are associated treatments impact glucose metabolism? Drugs 2009; 69:2:13-27.
  32. Dawson A. CPAP therapy of obstructive sleep apnea in type 2 diabetes improves glycemic control during sleep. J Clin Sleep Med. 2008; 4(6):538-542.
  33. Steiropoulos P, Papanas N, Nena E, Maltezos E, Bouros D. continuous positive airway pressure treatment in patients with sleep apnea: does it really improve glucose metabolism? Curr Diabetes Rev 2010; 6(3):156-166.
  34. Veber OA. Links between diabetes mellitus and sleep disorders: focusing on obstructive sleep apnea. Orv Hetil 2010; 151(1):8-16.
  35. Botros N, Concato J, Mohsenin V, Selim B, Doctor K, Yaggi HK. Obstructive sleep apnea as a risk factor for type 2 diabetes. Am J Med 2009; 122(12):1122-1127.
  36. Oktay B, Akbal E, Firat H, Ardic S, Kizilgun M. CPAP treatment in the coexistence of obstructive sleep apnea syndrome and metabolic syndrome, results of one year follow up. Acta Clin Belg 2009; 64(4):329-334.
  37. Einhorn D, Stewart DA, Erman MK, Gordon N, Philis- Tsimikas A, Casal E. Prevalence of sleep apnea in a population of adults with type 2 Diabetes mellitus. Endocrine Practice 2007; 13(4):355-362.
  38. Punjabi NM, Sorkin JD, Katzel LI, et al. Sleep-disordered breathing and insulin resistance in middle – aged and overweight men. Am J Respir Crit Care Med 2002; 165:677-682.
  39. Ip MS, Lam B, Ng MM, et al. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit care Med 2002; 165:670-676.
  40. American Academic of Sleep Medicine. International Classification of Sleep Diosrders: Diagnosic and Coding manual. 2nd ed. Westchester, IL. American Academy of Sleep Medicine, 2005.
  41. Spiegel K, Leproult R, L'Hermite-Baleriaux M, Copinschi G, Penev PD and Van Cauter E. Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin. J Clin Endocrinol Metab 2004; 89:5762-5771.
  42. Spath-Schwalbe E, Gofferje M, Kern W, Born J and Fehm HL. Sleep disruption alters nocturnal ACTH and cortisol secretory patterns. Biol Psychiatry. 1991; 29:575-584.
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