Indian Journal of Sleep Medicine

Register      Login

VOLUME 18 , ISSUE 3 ( July-September, 2023 ) > List of Articles

CASE REPORT

A Case of Obstructive Sleep Apnea Syndrome in Acromegaly

Neenu Najeeb, Sucheta Sunil Bhalerao, Vitthalrao Mohan Chintalwar

Keywords : Acromegaly, Coronavirus disease-2019, Guidelines, Obstructive sleep apnea syndrome, Pituitary microadenoma, Sleep practice

Citation Information : Najeeb N, Bhalerao SS, Chintalwar VM. A Case of Obstructive Sleep Apnea Syndrome in Acromegaly. Indian Sleep Med 2023; 18 (3):50-52.

DOI: 10.5005/jp-journals-10069-0121

License: CC BY-NC 4.0

Published Online: 23-11-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

A 78-year-old male patient was referred with a history of snoring and excessive daytime sleepiness for 3 years. The patient was diagnosed case of Acromegaly due to pituitary microadenoma. He was evaluated with polysomnography, which confirmed severe obstructive sleep apnea syndrome (OSAS). Acromegaly is an endocrine disorder resulting from excessive secretion of growth hormone in adults. They have a high prevalence of OSAS which often goes undiagnosed. We report one such case of OSAS in a diagnosed case of Acromegaly.


HTML PDF Share
  1. Rundo JV. Obstructive sleep apnea basics, Cleve Clin J Med 2019;86(9 Suppl 1):2–9. DOI: 10.3949/ccjm.86.s1.02.
  2. Pazarlı AC, Köseoğlu Hİ, Kutlutürk F, et al. Association of acromegaly and central sleep apnea syndrome. Turk Thorac J 2019;20(2):157–159. DOI: 10.5152/TurkThoracJ.2017.17003.
  3. Ntali G, Karavitaki N. Recent advances in the management of acromegaly. F1000Res 2015;4:F1000 Faculty Rev-1426. DOI: 10.12688/f1000research.7043.1.
  4. Lavrentaki A, Paluzzi A, Wass JA, et al. Epidemiology of acromegaly: Review of population studies. Pituitary 2017;20(1):4–9. DOI: 10.1007/s11102-016-0754-x.
  5. Capatina C, Wass JA. 60 Years of neuroendocrinology: Acromegaly. J Endocrinol 2015;226(2):T141–T160. DOI: 10.1530/JOE-15-0109.
  6. Melmed S. Acromegaly pathogenesis and treatment. J Clin Invest 2009;119(11):3189–3202. DOI: 10.1172/JCI39375.
  7. Melmed S. Medical progress: Acromegaly. N Engl J Med 2006;355(24):2558–2573. DOI: 10.1056/NEJMra062453.
  8. Pivonello R, Auriemma RS, Grasso LF, et al. Complications of acromegaly: Cardiovascular, respiratory and metabolic comorbidities. Pituitary 2017;20(1):46–62. DOI: 10.1007/s11102-017-0797-7.
  9. Flemons WW. Clinical practice. Obstructive sleep apnea. N Engl J Med 2002;347(7):498–504. DOI: 10.1056/NEJMcp012849.
  10. Kapur VK, Auckley DH, Chowdhuri S, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: An American academy of sleep medicine clinical practice guideline. J Clin Sleep Med 2017;13(3):479–504. DOI: 10.5664/jcsm.6506.
  11. Katznelson L, Laws ER Jr, Melmed S, et al. Endocrine Society. Acromegaly: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2014;99(11):3933–3951. DOI: https://doi.org/10.1210/jc.2014-2700.
  12. Melmed S, Casanueva FF, Klibanski A, et al. A consensus on the diagnosis and treatment of acromegaly complications. Pituitary 2013;16(3):294–302. DOI: 10.1007/s11102-012-0420-x.
  13. Taşbakan MS, Başoğlu ÖK, Yıldırım Şimşir I, et al. Obstructive sleep apnea characteristics in patients with well-controlled acromegaly and their compliance with positive airway pressure therapy. Turk J Med Sci 2017;47(5):1348–1353. DOI: 10.3906/sag-1612-139.
  14. Chemla D, Attal P, Maione L, et al. Impact of successful treatment of acromegaly on overnight heart rate variability and sleep apnea. J Clin Endocrinol Metab 2014;99(8):2925–2931. DOI: 10.1210/jc.2013-4288.
  15. Buyse B, Michels E, Bouillon R, et al. Relief of sleep apnoea after treatment of acromegaly: Report of three cases and review of the literature. Eur Respir J 1997;10(6):1401–1404. DOI: 10.1183/09031 936.97.10061401.
  16. Spicuzza L, Caruso D, Di Maria G. Obstructive sleep apnoea syndrome and its management. Ther Adv Chronic Dis 2015;6(5):273–285. DOI: 10.1177/2040622315590318.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.