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VOLUME 15 , ISSUE 4 ( October-December, 2020 ) > List of Articles
Vaishal S Shah, Vijay Sardana
Keywords : Acute ischemic stroke, Modified Rankin scale, Obstructive sleep apnea
Citation Information : Shah VS, Sardana V. Study of Obstructive Sleep Apnea in Acute Ischemic Stroke Patients. Indian Sleep Med 2020; 15 (4):60-64.
License: CC BY-NC 4.0
Published Online: 23-12-2020
Copyright Statement: Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.
Context: The study was done to assess the impact of obstructive sleep apnea (OSA) on acute ischemic stroke. Aims and objectives: To see the prevalence and severity of obstructive sleep apnea in patients with acute ischemic stroke in Rajasthan, to identify patients with acute ischemic stroke who should be screened for OSA, and to compare short-term neurological and functional outcomes in stroke patients with and without OSA. Settings and design: This is a prospective analytical study of 50 patients with acute ischemic stroke. Materials and methods: National Institute of Health Stroke Scale (NIHSS) and modified Rankin scale (mRS) scores were calculated at admission. After 10 days, all patients underwent minimum 4 hours of polysomnography. OSA was diagnosed when apneas hypopneas index (AHI) is more than 5 per hour. NIHSS scoring was done at discharge, and mRS scoring was done after 1 month. Statistical analysis used: Categorical variables were compared using the χ2 test and numerical variables using the t-test for independent samples. Statistical significance was set at 5%. Results: The prevalence of OSA was 36%. Obesity and high Epworth sleepiness scale were predictors of OSA. The distribution of stroke topography was similar in OSA and non-OSA groups. NIHSS and mRS were comparable in OSA and non-OSA groups. Difference in recovery of NIHSS was significant between OSA and non-OSA groups (1.16 and 2, respectively, p-value: 0.0017). There was a statistically significant difference in mRS at 1 month between OSA and non-OSA groups (2.88 and 2.53, respectively, p-value: 0.02). Conclusions: As poor neurological recovery during the hospital stay and poor functional recovery at 1 month in patients with acute ischemic stroke with OSA were found, our study highlights screening of OSA particularly for obese patients and patients with high Epworth sleepiness scale.
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