Indian Journal of Sleep Medicine

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VOLUME 15 , ISSUE 3 ( July-September, 2020 ) > List of Articles


Obstructive Sleep Apnea and Venous Thrombosis: Clinical Implications

S Ramnathan Iyer, Revati R Iyer

Keywords : Obstructive sleep apnea, Venous return, Venous thromboembolism

Citation Information : Iyer SR, Iyer RR. Obstructive Sleep Apnea and Venous Thrombosis: Clinical Implications. Indian Sleep Med 2020; 15 (3):51-53.

DOI: 10.5005/jp-journals-10069-0057

License: CC BY-NC 4.0

Published Online: 22-10-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Obstructive sleep apnea (OSA), although a disease of upper respiratory airway, has profound effects on body systems. The breathing abnormalities have effects on venous return. Pooling of blood in legs during apnea–hypopnea, coupled with hemodynamic changes and pathological cascades, favors thrombosis in legs and subsequent thromboembolism. An OSA has possible implications in vascular endothelial injury, stagnant blood flow, increased coagulability (Virchow\'s triad), and Trousseau\'s syndrome. An OSA suspicion must be high in all patients with venous thrombosis, particularly in those who have recurrent episodes of this disorder.

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