Indian Journal of Sleep Medicine

Register      Login

VOLUME 14 , ISSUE 4 ( October-December, 2019 ) > List of Articles

CASE REPORT

A 13-year-old Girl with Hypercapnic Respiratory Failure

Keywords : Hypoventilation, Idiopathic, Noninvasive ventilation

Citation Information : A 13-year-old Girl with Hypercapnic Respiratory Failure. Indian Sleep Med 2019; 14 (4):76-78.

DOI: 10.5005/jp-journals-10069-0044

License: CC BY-NC 4.0

Published Online: 01-12-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Late-onset congenital central hypoventilation syndrome (LO-CCHS) is a rare entity, with scant literature. In view of low prevalence and poor awareness in both patients and doctors, it is often diagnosed late or, worse, misdiagnosed as an obstructive airway disease. Timely diagnosis of central hypoventilation is necessary to prevent hypercapnia, acidosis, and hypoxemia, which can adversely affect the cardiovascular and neurocognitive function. Here we report an interesting case of a young nonobese female who had history of multiple intensive care unit (ICU) admissions for her hypercapnic respiratory failure.


PDF Share
  1. Brown LK. Hypoventilation syndromes. Clin Chest Med 2010;31(2): 249–270. DOI: 10.1016/j.ccm.2010.03.002.
  2. Dosier LBM, Vaughn BV, Fan Z. Sleep disorders in childhood neurogenetic disorders. Children (Basel) 2017;4(9):82.
  3. Magalhães J, Madureira N, Medeiros R, et al. Late-onset congenital central hypoventilation syndrome and a rare PHOX2B gene mutation. Sleep Breath 2015;19(1):55–60. DOI: 10.1007/s11325-014-0996-7.
  4. Gothi D, Joshi JM. Late onset hypoventilation syndrome: is there a spectrum of idiopathic hypoventilation syndromes? Indian J Chest Dis Allied Sci 2005;47(4):293–298.
  5. Marcus CL. Sleep-disordered breathing in children. Am J Respir Crit Care Med 2001;164(1):16–30. DOI: 10.1164/ajrccm.164.1.2008171.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.