Indian Journal of Sleep Medicine

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VOLUME 13 , ISSUE 2 ( April-June, 2018 ) > List of Articles


Mirtazapine Induced Parasomnia Overlap Disorder

Mahismita Patro, Ram B Sah, Sammer Vaidya

Keywords : Nonrapid eye movement (NREM) parasomnia, POD, Rapid eye movement (REM), Sleep behaviour disorder (RBD)

Citation Information : Patro M, Sah RB, Vaidya S. Mirtazapine Induced Parasomnia Overlap Disorder. Indian Sleep Med 2018; 13 (2):36-38.

DOI: 10.5005/jp-journals-10069-0022

License: NA

Published Online: 01-10-2018

Copyright Statement:  NA


A 70-year-old non-addict man with the history of diabetes, hypertension and allergic rhinitis was referred for abnormal behavior during the night. The behaviors included shouting, punching, walking during sleep, leaving the house and dream enactment. He also had history of snoring and excessive daytime sleepiness, suspicious of obstructive sleep apnea (OSA). He was suffering from depression for which he was on antidepressants, i.e., mirtazapine, sertraline and olanzapine by a psychiatrist. The abnormal sleep behaviors developed after start of mirtazapine. After ruling out all other causes, he was finally diagnosed to be suffering from drug-induced parasomnia overlap disorder (POD) caused by mirtazapine along with OSA based on international classification of sleep disorders–3rd edition (ICSD-3). He had resolution of the parasomnia episodes after stoppage of mirtazapine.

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