Correlation of Body Habitus with Severity of Obstructive Sleep Apnea: A Prospective Study from a Single Institution
Madhumita Kumar, Uttumadathil G Unnikrishnan
Apnea-hypopnea index, Body mass index, Neck circumference, Obstructive sleep apnea
Citation Information :
Kumar M, Unnikrishnan UG. Correlation of Body Habitus with Severity of Obstructive Sleep Apnea: A Prospective Study from a Single Institution. Indian Sleep Med 2017; 12 (2):7-11.
Objectives: To correlate body habitus with severity of obstructive sleep apnea (OSA) in Indian subjects.
Subjects: Prospective study. Consecutive patients with OSA during the period 2013 to 2016 were included.
Materials and methods: Body mass index (BMI), neck circumference (NC), and Epworth sleepiness scale (ESS) were recorded and their association with severity of OSA as graded by apnea-hypopnea index (AHI) was analyzed
Results: Totally 100 patients were included; 91 were male. Mean age was 46.58 ± 12.92 years. Abnormal BMI, NC, and ESS were observed in 67.3, 33.6 and 52.7% respectively. Moderate and severe forms of OSA were found in 26 and 54% respectively. Severe OSA was more common in men (56 vs 33.3%; p = 0.15). There was a strong correlation of OSA with BMI (r = 0.378; p < 0.001), NC (r = 0.502; p < 0.001), and ESS (r = 0.304; p = 0.002).
Conclusions: Obstructive sleep apnea in Indian patients has strong correlation with male sex and indices of body habitus.
Chung F, Yang Y, Liao P. Predictive performance of STOP-Bang score for obstructive sleep apnoea in obese patients. Obes Surg 2013 Dec;23(12);2050-2057.
Guilleminault C, Tilkian A, Dement WC. The sleep apnea syndromes. Annu Rev Med 1976;27:465-484.
Isono, S.; Remmers, JE. Anatomy and physiology of upper airway obstruction. In: Krygger MH, Roth T, Dement WC, editors. Principles and practice of sleep medicine, 2nd ed. Philadelphia, PA: WB Saunders; 1994. pp. 642-656.
Robinson, A.; Guilleminault, C. Obstructive sleep syndrome. In: Chokroverty S, editor. Sleep disorders medicine: basic science, technical considerations, and clinical aspects, 2nd ed. Woburn: Butterworth Heinemann; 1999. pp. 331-354.
Smirne S, Iannaccone S, Ferini-Strambi L, Comola M, Colombo E, Nemni R. Muscle fibre type and habitual snoring. Lancet 1991;337:597-599.
Sher AE. Obstructive sleep apnoea syndrome: a complex disorder of the upper airway. Otolaryngol Clin North Am 1990 Aug;23(4):593-608.
Ogretmenoglu O, Suslu AE, Yucel OT, Onerci TM, Sahin A. Body fat composition: a predictive factor for obstructive sleep apnea. Laryngoscope 2005 Aug;115(8):1493-1498.
Vana KD, Silva GE, Goldberg R. Predictive abilities of the STOP-Bang and Epworth Sleepiness Scale in identifying sleep clinic patients at high risk for obstructive sleep apnea. Res Nurs Health 2013 Feb;36(1):84-94.
Farney RJ, Walker BS, Farney RM, Snow GL, Walker JM. The STOP-bang equivalent model and prediction of severity of obstructive sleep apnea; relation to polysomnographic measurements of the apnea/hypopnea index. J Clin Sleep Med 2011 Oct;7(5):459-465.
American Academy of Sleep Medicine. Sleep related breathing disorders in adults: recommendations for syndrome definitions and measurements techniques in clinical research. Sleep 1999 Aug;22(5):667-689.
Ahbab S, Ataoglu HE, Tuna M, Karasulu L, Çetin F, Temiz LU, Yenigün M. Neck circumference, metabolic syndrome and obstructive sleep apnoea syndrome; evaluation of possible linkage. Med Sci Monit 2013 Feb;19:111-117.
Flemons WW. Clinical practice. Obstructive sleep apnea. N Engl J Med 2002 Aug;347(7):498-504.
Kawaguchi Y, Fukumoto S, Inaba M, Koyama H, Shoji T, Shoji S, Nishizawa Y. Different impacts of neck circumference and visceral obesity on the severity of obstructive sleep apnea syndrome. Obesity (Silver Spring) 2011 Feb;19(2): 276-282.
Peppard PE, Young T, Palta M, Dempsey J, Skatrud J. Longitudinal study of moderate weight change and sleep disordered breathing. JAMA 2000 Dec;284(23):3015-3021.
Iber, C.; Ancoli-Israel, S.; Chesson, AL Jr.; Quan, SF. The AASM Manual for the scoring of sleep and associated events: rules terminology and technical specifications. Westchester, IL: American Academy of Sleep Medicine; 2007.
Plywaczewski R, Bielen P, Bednarek M, Jonczak L, Gorecka D, Sliwinski P. [Influence of neck circumference and body mass index on obstructive sleep apnoea severity in males]. Pneumonol Alergol Pol 2008;76(5):313-320.
Sakakibara H, Tong M, Matsushita K, Hirata M, Konishi Y, Suetsugu S. Cephlometric abnormalities in non-obese and obese patients with obstructive sleep apnoea. Eur Respir J 1999 Feb;13(2):403-410.
Caples SM, Gami AS, Somers VK. Obstructive sleep apnoea. Ann Intern Med 2005 Feb;142(3):187-197.
Vgontzas AN. Does obesity play a major role in the pathogenesis of sleep apnoea and its associated manifestations via inflammation, visceral adiposity and insulin resistance? Arch Physiol Biochem 2008;114(4):211-223.
Soylu AC, Levent E, Sariman N, Yurtlu S, Alparslan S, Saygi A. Obstructive sleep apnea syndrome and anthropometric obesity indexes. Sleep Breath 2012 Dec;16(4):1151-1158.
Medeiros CA, Bruin VM, Castro-Silva C, Bruin PF. Neck circumference, a bedside clinical feature related to mortality of acute ischemic stroke. Rev Assoc Med Bras 2011 Sept- Oct;57(5):559-564.
Martins AB, Tufik S, Moura SM. Physiopathology of obstructive sleep apnoea-hypopnoea syndrome. J Bras Pneumol 2007;33(1):93-100.
Davies RJO, Stradling JR. The relationship between neck circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome. Eur Respir J 1990 May;3(5):509-514.
Katz I, Stradling JR, Slutsky AS, Zamel N, Hoffstein V. Do patients with obstructive sleep apnoea have a thick neck? Am Rev Respir dis 1990 May;141(5 Pt 1):1228-1231.
Sun Y, Ning Y, Huang L, Lei F, Li Z, Zhou G, Tang X. Polysomnographic characteristics of day time sleepiness in obstructive sleep apnoea syndrome. Sleep Breath 2012 Jun;16(2):375-381.
Chen R, Xiong KP, Lian YX, Huang JY, Zhao MY, Liu CF. Daytime sleepiness and its determining factors in Chinese obstructive sleep apnoea patients. Sleep Breath 2011;15(1): 129-135.
Mediano O, Barcelo A, de la Pena M, Gozal D, Agusti A, Barbe F. Daytime sleepiness and polysomnographic variables in sleep apnoea patients. Eur Respir J 2007 Jul;30(1):110-113.