Indian Journal of Sleep Medicine

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VOLUME 11 , ISSUE 4 ( October-December, 2016 ) > List of Articles


Association of Hypothyroidism in Obstructive Sleep Apnea Syndrome

Shailesh Kalamkar, Unnati D. Desai

Keywords : Apnea-hypopnea index (AHI), Polysomnography, Thyroid function tests (TFT), OSAS, Hypothyroid treatment.

Citation Information : Kalamkar S, Desai UD. Association of Hypothyroidism in Obstructive Sleep Apnea Syndrome. Indian Sleep Med 2016; 11 (4):145-150.

DOI: 10.5958/0974-0155.2016.00021.8

License: NA

Published Online: 01-12-2014

Copyright Statement:  NA


Background: Hypothyroidism and obstructive sleep apnea syndrome (OSAS) are common comorbid conditions with overlapping clinical presentation. We decided to study the association of hypothyroidism in our OSAS patients. Methodology: This observational study included 108 patients with clinical features suggesting OSAS. The clinical details were noted; Polysomnography (PSG) and thyroid function tests (TFT) were done. Qualitative and quantitative data was analyzed with appropriate tests. Results: Seventy-two (66.7%) men and 36 (33.3%) women were included. PSG confirmed OSAS in 78 (72.2%). The severity of OSAS was mild, moderate, severe in 30 (38%), 28 (36%), 20 (26%) respectively. Thirteen (12%) had hypothyroidism; subclinical in 2 (15%) and clinical in 11 (85%). Only 2 (15%) were on optimal medical treatment. Hypothyroidism was seen in 11(14%) of OSAS, against in 2(7%) of the non-OSAS group. OSAS was found in 11(85%) of hypothyroid, against in 67 (71%) of the Euthyroid group. A statistically significant association between OSAS and hypothyroidism treatment was observed. Conclusion: The prevalence of hypothyroidism was higher in OSAS; though statistically insignificant. Association between OSAS and hypothyroidism treatment was statistically significant.

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